At Leo Corps our team of clinical, scientific, administrative, and consulting experts are dedicated to providing our research and development products such as formulated laboratory reagents, Cord-Derived Regenerative Cells, Bone Marrow Regenerative cells, Extracellular Vesicles, Peripheral blood-derived cells, cell proliferation and cellular-based assay kits and products to advance human disease research that will ultimately improve patient outcomes and science.
Stem Cell Products
Basic Research
Cell Therapy
Drug Discovery
Solutions
Basic scientific research is at the heart of advances in medicine and patient care. In order to perform groundbreaking and paradigm-shifting work, scientists at pharmaceutical companies, government facilities, and academic institutions require the highest quality resources. Our proprietary Cord-Derived Regenerative Cells, Extracellular Vesicle, and research reagents provide a reliable, high-quality source of human-derived material for laboratory studies. All of our products are processed under exceptional, high-quality R&D standards with donor consent in our state-of-the-art laboratories and are evaluated and tested at CLIA-approved and FDA-registered and audited medical labs by expert scientific and laboratory staff. We pride ourselves on providing the highest quality and reliable products on the market for all your research needs.
Hematopoietic Cellular therapy
Hematopoietic stem cells have long been of interest for their possible therapeutic applications. Umbilical cord blood was identified as a third source of these stem cells after the discovery of bone marrow and peripheral blood. It has since been designated as a drug by the United States FDA (Food and Drug Administration), meaning it must meet strict federal regulations.
Stem cells are critical for both scientific discovery and for stem cell transplantation into sick patients as a therapeutic agent. However, stem cells are rarely assessed for quality, identity, and purity before their use. This is important when considering that effective therapies would likely need to be robust and reproducible on a large scale. At the same time, successful scientific experiments require consistent cell types and quantities.
To remove this obstacle, Leo Corps and affiliative companies offers both the largest selection of hematopoietic stem cell therapy assays on the market and also human cell lines. These products are applicable to different stages of the stem cell transplantation process, such as separating out high quality stem cells, as well as monitoring patients after the transplantation procedure. It is our goal to set the bar as high as possible so that researchers receive the highest quality, and most effective products available.
Please contact us for more details.
Immunotherapy
Immunotherapy is fast becoming an effective tool to treat different types of cancer. Identifying and understanding the interactions between and among immune cells is important in developing immunotherapy tools. For example, dendritic cells or mesenchymal stem cells interact with immune cells in an intricate manner in graft-versus-host disease. Striking the right balance of immune cells could replace more traditional approaches in cancer and other human diseases.
At Leo Corps and affiliative companies, we are proud to provide the highest quality products and tools for your research projects to better understand the science behind immunotherapy. In addition, we help to define these interactions and measure the response obtained using either mixtures of cells or purified sub-populations of cells.
Regenerative Medicine
Regenerative medicine refers to a type of therapy where cells or tissues, including bones, muscles, and tendons, are repaired following injury. These cells and tissues are generally derived from mesenchymal cells.
An ongoing challenge in the field is to identify a robust cell source and subsequently quantitatively measuring its functions and phenotype.
Leo Corps and affiliative companies offer cutting-edge assays that answer these questions, especially in regards to mesenchymal stem cells. Whether cells are used for basic scientific discovery or for therapies, it is critical to definitively characterize them.
While MSCs (mesenchymal stem cells) are able to repeatedly expand, it is recommended to use MSCs as close to the native cell as possible. MSCGlo™ Real Time can aid in characterizing your MSC cell lines. It can also aid in determining their doubling time to improve the reproducibility of your results. We set the bar as high as possible so that researchers receive the highest quality products on the market.
While regenerative medicine remains an exciting field with enormous potential, therapies using EVs (extracellular vesicles), MSCs, HSCs (hematopoietic stem cells) or VSFs (vesicular secretome factions) are understudied. Despite the biological and regulatory complexity of these therapeutic targets, we must continue the search for scalable and reproducible purification protocols based on robust risk-based approaches. We must also elucidate the mechanisms of action through qualified potency assays in disease-relevant in vitro and in vivo models. If GMP (Good Manufacturing Practice) protocols and regulatory requirements can be applied to therapies derived from EVs, MSCs, HSCs or VSFs, we will see a spike in human clinical trials using these products. Regulatory compliance is an integral part of a stable manufacturing process, and if indeed “the process is the product,” this compliance will be critical in the large-scale pharmaceutical production with the ultimate goal of creating reproducible and effective therapies.
Hematopoietic stem cells have long been of interest for their possible therapeutic applications. Umbilical cord blood was identified as a third source of these stem cells after the discovery of bone marrow and peripheral blood. It has since been designated as a drug by the United States FDA (Food and Drug Administration), meaning it must meet strict federal regulations.
Stem cells are critical for both scientific discovery and for stem cell transplantation into sick patients as a therapeutic agent. However, stem cells are rarely assessed for quality, identity, and purity before their use. This is important when considering that effective therapies would likely need to be robust and reproducible on a large scale. At the same time, successful scientific experiments require consistent cell types and quantities.
To remove this obstacle, Leo Corps and affiliative companies offers both the largest selection of hematopoietic stem cell therapy assays on the market and also human cell lines. These products are applicable to different stages of the stem cell transplantation process, such as separating out high quality stem cells, as well as monitoring patients after the transplantation procedure. It is our goal to set the bar as high as possible so that researchers receive the highest quality, and most effective products available.
Please contact us for more details.
Immunotherapy
Immunotherapy is fast becoming an effective tool to treat different types of cancer. Identifying and understanding the interactions between and among immune cells is important in developing immunotherapy tools. For example, dendritic cells or mesenchymal stem cells interact with immune cells in an intricate manner in graft-versus-host disease. Striking the right balance of immune cells could replace more traditional approaches in cancer and other human diseases.
At Leo Corps and affiliative companies, we are proud to provide the highest quality products and tools for your research projects to better understand the science behind immunotherapy. In addition, we help to define these interactions and measure the response obtained using either mixtures of cells or purified sub-populations of cells.
Regenerative Medicine
Regenerative medicine refers to a type of therapy where cells or tissues, including bones, muscles, and tendons, are repaired following injury. These cells and tissues are generally derived from mesenchymal cells.
An ongoing challenge in the field is to identify a robust cell source and subsequently quantitatively measuring its functions and phenotype.
Leo Corps and affiliative companies offer cutting-edge assays that answer these questions, especially in regards to mesenchymal stem cells. Whether cells are used for basic scientific discovery or for therapies, it is critical to definitively characterize them.
While MSCs (mesenchymal stem cells) are able to repeatedly expand, it is recommended to use MSCs as close to the native cell as possible. MSCGlo™ Real Time can aid in characterizing your MSC cell lines. It can also aid in determining their doubling time to improve the reproducibility of your results. We set the bar as high as possible so that researchers receive the highest quality products on the market.
While regenerative medicine remains an exciting field with enormous potential, therapies using EVs (extracellular vesicles), MSCs, HSCs (hematopoietic stem cells) or VSFs (vesicular secretome factions) are understudied. Despite the biological and regulatory complexity of these therapeutic targets, we must continue the search for scalable and reproducible purification protocols based on robust risk-based approaches. We must also elucidate the mechanisms of action through qualified potency assays in disease-relevant in vitro and in vivo models. If GMP (Good Manufacturing Practice) protocols and regulatory requirements can be applied to therapies derived from EVs, MSCs, HSCs or VSFs, we will see a spike in human clinical trials using these products. Regulatory compliance is an integral part of a stable manufacturing process, and if indeed “the process is the product,” this compliance will be critical in the large-scale pharmaceutical production with the ultimate goal of creating reproducible and effective therapies.
A key step in the therapeutic development pipeline is rigorous experimentation on human tissue. Leo Corps supports scientists in commercial, government, and academic settings by providing quality-controlled, reliable human samples for in vitro and ex vivo manipulation with target therapeutics. The fast, consistent turnaround of our quality assured-biospecimens will facilitate the progression of candidate therapeutics from the laboratory to the clinic.