CytoCord™

Mesenchymal stem cells are adult stem cells that can be isolated from various sources. These sources include adipose tissue, the umbilical cord, and bone marrow. Purified MSCs exhibit a phenotype similar to fibroblast and differentiate based on the site of origin. For example, an MSC isolated from the bone marrow will differentiate into bone marrow-related cells. MSCs are able to repair injured tissues and may be important in immunomodulation, making them valuable in both basic science and translational studies.

The technology behind Cytocord™ has been validated to deliver the highest purity and quality to ensure your research protocols are reliable.

Cytocord™ is a secretome-based product that contains collagen, elastin, and hyaluronic acid.

Umbilical Cord Matrix/Wharton’s Jelly Nucleated Native product contains both growth factors and an assortment of cell types, including mesenchymal stem cells, epithelial cells, and endothelial cells. These cell types can secrete anti-inflammatory and immunomodulatory properties that can then be optimized to reach your clinical research needs.

All donors go through a rigorous screening process, as determined by the guidelines and regulations listed by the FDA and the American Association of Tissue Banks (AATB). Maternal blood for the fresh umbilical cord tissue must be negative for HIV (Human Immunodeficiency Virus),  HBV (Hepatitis B), HCV (Hepatitis C), CMV IgM (cytomegalovirus antibodies), Syphilis, WNV (West Nile Virus), HTLV I/II (Human T-Cell Lymphotropic Virus Types I and II), and Chagas Disease. The consented umbilical cord ships to our cell manufacturing facility where primary cells are processed and analyzed. Parameters including cell phenotype, viability, purity, and cell count are checked to meet the FDA’s gold standard for biopharma companies, ensuring high-quality cells are characterized and purified.

The umbilical cord matrix does not express HLA-DR, therefore, it is immune privileged.

All R&D (Research and Development) birth tissue products come with a certificate of analysis and are ethically sourced from donated birthing tissues such as umbilical cords and placentas from healthy full-term deliveries. Comprehensive medical and social histories of the donor are obtained, and tissues are procured, processed, and tested to meet or often exceed market standards.

Phenotyping analysis of native MSCs by flow cytometry

Using MSCs in clinical research requires a thorough understanding of mechanisms and processes underlying their differentiation into specific cell types, as well as the phenotypic validation of these MSC-derived cells. The Cytogen is based on ISCT (International Society for Cellular Therapy) markers for human MSCs and helps to easily perform standardized phenotyping of culture-expanded MSCs or native MSCs by flow cytometry. For researchers aiming to analyze and characterize their MSC cell lines and differentiated cells, Leo Corps and affiliative companies can provide a robust protocol of flow cytometry and recommended reagents. Please contact us for more details.

Weight	1 lbs
Size	0.5 cc (1 Million), 1cc (2 Milion), 2cc ( 3 Million )
Manufacturer	Novoxa
Storage	Sterile Vial
U/M	0.5 cc (1 Million) , 1cc (2 Milion) , 2cc ( 3 Million )
Shipping Temp/Condition	Frozen (-81 celcius)
Storage Temp	Frozen (-133 celcius or lower)
Media Expiry, 4C	N/A
Media Expiry, -20C	N/A
Preservative	DMSO (5%)

Unless otherwise specifically indicated, Leo corps and its affiliative products and services are for research use only and not for therapeutic or diagnostic use. Cytocord and All other trademarks mentioned in this document are the property of their respective owners and are used for identification purposes only. Copyright © 2020 Novoxa Biotech, Inc. and/or its affiliates. CytoCord is a high-quality product manufactured by Novoxa Biotech, Inc. All rights reserved.